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研究成果

2024年

1)Kensuke Sato, Mariko Hara-Chikuma, Masato Yasui, Joe Inoue, Yun-Gi Kim.

Sufficient Water Intake Maintains the Gut Microbiota and Immune Homeostasis and Promotes Pathogen Elimination.

ISCIENCE (2024), doi: https://doi.org/10.1016/j.isci.2024.109903.

2)Ogasawara J, Matsumoto N, Takeuchi Y, Yamashiro K, Yasui M, Ikegaya Y.

Lengthened circadian rhythms in mice with self-controlled ambient light intensity. 

Sci Rep . 2024 Apr 2;14(1):7778.  doi: 10.1038/s41598-024-58415-x. (2024)

3)Yamaguchi S, Irie J, Mitsuishi M, Uchino Y, Nakaya H, Takemura R, Inagaki E, Kosugi S, Okano H, Yasui M, Tsubota K, Hayashi K, Yoshino J, Itoh H.

Safety and efficacy of long-term nicotinamide mononucleotide supplementation on metabolism, sleep, and nicotinamide adenine dinucleotide biosynthesis in healthy, middle-aged Japanese men.

Endocr J. 2024 Feb 28;71(2):153-169. doi: 10.1507/endocrj.EJ23-0431. Epub 2024 Jan 6. (2024)

4)Morishita T, Nishizaki N, Taniguchi S, Sakai S, Kimura T, Mita M, Nakagawa M, Endo A, Ohtomo Y, Yasui M, Shimizu T, Sasabe J. Plasma D-asparagine and the D/L-serine ratio reflect chronic kidney diseases in children regardless of physique. Amino Acids. 2024 Jun 6;56(1):38. doi: 10.1007/s00726-024-03400-x. 

5)Yamamoto E, Joo K, Lee J, Sansom MSP, Yasui M. Molecular mechanism of anion permeation through aquaporin 6. Biophys J. 2024 Jun 17:S0006-3495(24)00410-7. doi: 10.1016/j.bpj.2024.06.013.

2023年

1)Gonda Y, Matsuda A, Adachi K, Ishii C, Suzuki M, Osaki A, Mita M, Nishizaki N, Ohtomo Y, Shimizu T, Yasui M, Hamase K, Sasabe J.

Mammals sustain amino acid homochirality against chiral conversion by symbiotic microbes.

Proc Natl Acad Sci U S A. 120(15): e2300817120. DOI: 10.1073/pnas.2300817120. (2023) 

2)Murakami A, Tsuji K, Isoda M, Matsuo M, Abe Y, Yasui M, Okamura H, Tominaga K.

Prolonged Light Exposure Induces Circadian Impairment in Aquaporin-4-Knockout Mice.

J Biol Rhythms. 38(2):208-214. DOI: 10.1177/07487304221146242. (2023) 

3)Urushihata T, Takuwa H, Takahashi M, Kershaw J, Shibata S, Nitta N, Tachibana Y, Yasui M, Higuchi M, Obata T.

Distribution of intraperitoneally administered deuterium-labeled water in aquaporin-4-knockout mouse brain after middle cerebral artery occlusion.

Front Neurosci. 16:1071272. DOI: 10.3389/fnins.2022.1071272(2023)

4)Wang Y, Suzuki R, Fujii A, Ieki K, Goda W, Yasui M, Abe Y.

A tyrosine-based YXXΦ motif regulates the degradation of aquaporin-4 via both lysosomal and proteasomal pathways and is functionally inhibited by a 10-amino-acid sequence within its C-terminus.

FEBS J. 290(10):2616-2635. DOI: 10.1111/febs.16717(2023)

5)Osaki A, Aoyama M, Mita M, Hamase K, Yasui M, Sasabe J.

Endogenous d-serine exists in the mammalian brain independent of synthesis by serine racemase.

DOI: 10.1016/j.bbrc.2022.12.037

6)  Kojić D, Simonova A, Yasui M. 
Removal of the ambient air features from fourier-Transform near-Infrared spectra.
J Quant Spectrosc Radiat Transf. 301, Article 108538.

7)  Shinotsuka T, Miyazawa T, Karasawa K, Ozeki Y, Yasui M, Nuriya M.
Stimulated Raman scattering microscopy reveals a unique and steady nature of brain water dynamics, Cell Rep Methods, 2023 Jul 5;3(7):100519. Doi:10.1016

 

2022年

1)Oda R, Shou J, Zhong W, Ozeki Y, Yasui M, Nuriya M.

Direct Visualization of General Anesthetic Propofol on Neurons by Stimulated Raman Scattering Microscopy.

iScience. 2022 Feb 17;25(3):103936. doi: 10.1016/j.isci.2022.103936.

2)Ishida K, Yamada K, Nishiyama R, Hashimoto T, Nishida I, Abe Y, Yasui M, Iwatsubo T.

Glymphatic system clears extracellular tau and protects from tau aggregation and neurodegeneration.

J Exp Med. 2022 Mar 7;219(3):e20211275. doi: 10.1084/jem.20211275.

3)Nakamura K, Karasawa K, Yasui M, Nuriya M.

Probing the Spatiotemporal Dynamics of Oxytocin in the Brain Tissue Using a Simple Peptide Alkyne-Tagging Approach.

Anal Chem., 94(35): 11990-11998.

4)Shi Y, Yasui M, Hara-Chikuma M.

AQP9 transports lactate in tumor-associated macrophages to stimulate an M2-like polarization that promotes colon cancer progression.

Biochem Biophys Rep. 2022 Aug 7;31:101317. doi: 10.1016/j.bbrep.2022.101317.

eCollection 2022 Sep. PMID: 35967760

 

5)Abe Y, Yasui M.

Aquaporin-4 in Neuromyelitis Optica Spectrum Disorders: A Target of Autoimmunity in the Central Nervous System.

Biomolecules. 2022 Apr 17;12(4):591. doi: 10.3390/biom12040591. PMID: 35454180

 

6)Imaizumi A, Obata T, Kershaw J, Tachibana Y, Abe Y, Shibata S, Nitta N, Aoki I, Yasui M, Higashi T.

Quantitative measurement of diffusion-weighted imaging signal using expression-controlled aquaporin-4 cells: Comparative study of 2-compartment and diffusion kurtosis imaging models.PLoS One. 2022 Apr 19;17(4):e0266465.

doi: 10.1371/journal.pone.0266465. eCollection 2022. PMID: 35439261

 

2021年

1)Nuriya M, Ashikari Y, Iino T, Asai T, Shou J, Karasawa K, Nakamura K, Ozeki Y, Fujimoto Y, Yasui M.

Alkyne-Tagged Dopamines as Versatile Analogue Probes for Dopaminergic System Analysis.

Anal Chem. 2021 Jul 13;93(27):9345-9355. doi: 10.1021/acs.analchem.0c05403. Epub 2021 Jul 1.

2)Ogasawara J, Ikenoue S, Yamamoto H, Sato M, Kasuga Y, Mitsukura Y, Ikegaya Y, Yasui M, Tanaka M, Ochiai D.

Deep neural network-based classification of cardiotocograms outperformed conventional algorithms.

Sci Rep. 2021 Jun 28;11(1):13367. doi: 10.1038/s41598-021-92805-9.

3)Ramadhanti J, Yamada T, Yasui M, Nuriya M.

Differentially regulated pools of aquaporin-4 (AQP4) proteins in the cerebral cortex revealed by biochemical fractionation analyses.

J Pharmacol Sci. 2021 May;146(1):58-64. doi: 10.1016/j.jphs.2021.03.003. Epub 2021 Mar 17.

4)Suzuki M, Sujino T, Chiba S, Harada Y, Goto M, Takahashi R, Mita M, Hamase K, Kanai T, Ito M, Waldor MK, Yasui M, Sasabe J.

Host-microbe cross-talk governs amino acid chirality to regulate survival and differentiation of B cells.

Sci Adv. 2021 Mar 3;7(10):eabd6480. doi: 10.1126/sciadv.abd6480. Print 2021 Mar.

5)Glady A, Vandebroek A, Yasui M.

Human keratinocyte-derived extracellular vesicles activate the MAPKinase pathway and promote cell migration and proliferation in vitro. Inflamm Regen.

2021 Feb 2;41(1):4. doi: 10.1186/s41232-021-00154-x.

6)Chau S, Fujii A, Wang Y, Vandebroek A, Goda W, Yasui M, Abe Y.

Di-lysine motif-like sequences formed by deleting the C-terminal domain of aquaporin-4 prevent its trafficking to the plasma membrane. Genes Cells.

2021 Mar;26(3):152-164. doi: 10.1111/gtc.12829.

7)Vandebroek A, Yasui M.

Cu 1+, but not Cu 2+ is capable of inhibition of AQP4 permeability in an in vitro CHO cell based model.

Biochem Biophys Rep. 2021 Sep 14;28:101132. doi: 10.1016/j.bbrep.2021.101132. PMID: 34557603 

8)Ishikawa T, Yasui M.

[Water Transportation During Cerebral Edema Formation and Aquaporin-4]

Brain Nerve. 2021 Sep;73(9):983-989. doi: 10.11477/mf.1416201875.

9)Shou J, Oda R, Hu F, Karasawa K, Nuriya M, Yasui M, Shiramizu B, Min W, Ozeki Y.

Super-multiplex imaging of cellular dynamics and heterogeneity by integrated stimulated Raman and fluorescence microscopy. iScience. 2021 Jul 9;24(8):102832. doi: 10.1016/j.isci.2021.102832.

10)Kato Y, Munćan J, Tsenkova R, Kojić D, Yasui M, Fan JY, Han JY.

Aquaphotomics Reveals Subtle Differences between Natural Mineral, Processed and Aged Water Using Temperature Perturbation Near-Infrared Spectroscopy. Appl. Sci. 11(19): 9337 (2021)

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