Department of Pharmacology, Keio University School of Medicine
Life / Flowing Order - Complex Pharmacology -
Life Science of Water Molecules/Aquaporin Research/Aquaphotomics/Nonlinear Optics/Neuroscience
Basic Principles of the Department
Inheriting the spirit of drug discovery and leading new pharmacology
What does "alive" mean? It sounds very simple, but when I try to answer it, I think it's a surprisingly difficult and profound theme. We are fortunate to live on a very beautiful planet called "Earth". It is no exaggeration to say that life on earth depends on "water" and "air (gas)", whether or not life exists outside of the earth. In fact, nearly 70% of the human body is made up of water molecules (H2O). "I want to get closer to the essence of life phenomena by deepening my understanding of water." In other words, we aim to "recapture life phenomena from the behavior of water molecules". Specifically, in addition to conventional molecular/cell biology and biochemical methods, we will incorporate 1) imaging of water molecules using cutting-edge optical technology, and 2) computer simulation of water molecule dynamics. to understand the role of water in living organisms. We believe that these studies will lead to a more accurate understanding of drug absorption in the gastrointestinal epithelium and blood-brain barrier and pharmacokinetics in brain tissue in the field of pharmacology as well.
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